
The Operating Manual for Your Nervous System
Embrace ‘state over story’ to shift your thoughts and overcome anxiety
Feb 24, 2023 · 9 min readUpdated Mar 16, 2026
Sponsored By: Future London Academy
This article is brought to you by MBA for Design Leaders at Future London Academy. Learn Business Strategy, Finance, and Leadership from Spotify, Wolff Olins, Monzo, Pentagram, AKQA, and others. Only 30 spots are available.
Techniques for tactical mindfulness—using mind-based or “top-down” tools to influence our thoughts and feelings—have exploded in popularity.
But when our nervous systems are hijacked and adrenaline is coursing through our veins, unless we have thousands of hours of mindfulness training, it can be hard to avoid panic mode, let alone drop into meditation.
Fortunately, it is possible (and, as I will argue, far more efficient) to leverage your physiology—known as “bottom-up” practices—by using breathwork to self-regulate and positively impact your internal state in real-time.
The cultivation of calm
The human nervous system is one of the most technologically advanced operating systems in the known universe. It is not only responsible for our energy levels (aka productivity) and capacity for relaxation, but it is also the filter through which we experience the world and people around us.
You would think this remarkable network of neurological hardware would have a complex instruction manual. Fortunately, it is more simple to learn than you might think.
Many of us find it challenging to think clearly when our nervous system has been hijacked by a trigger or an intense situation. Perhaps you experienced nervous energy, even anxiety, before an important conversation or presentation, which hindered your capacity to give it your best or be fully present. Or maybe you felt lethargy creep in when you sat down for a deep workflow session.
Making matters worse is that unproductive thought loops and feelings exacerbate the issue. These reactive states are the underlying cause of ineffectiveness, reactivity, conflict, and regrettable decision-making.
Luckily, there is a zero-cost solution to this quandary—an always-accessible operating manual for your nervous system that is more effective than any prescription drug, with no unwanted side effects. In fact, it has been under your nose since you were born: your breath.
I’m going to explain the science of how breathwork functions, and then I’ll give you some actionable exercises so that you can do it yourself. Drawing from recent discoveries in neurobiology, there are two concepts that will empower you to be more effective in aligning the state of your nervous system with your desired state of grounded calm or clear focus.
- The nervous system remote: using the bottom-up method of our breath to impact blood chemistry, which shifts the thoughts and feelings that arise
- If [this] then [breathe]: two protocols you can use to effectively leverage your biology to up- or down-regulate your state, accessing either focus or calm as required
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The nervous system operating manual
How is your breath right now? Take a moment to tune in. There’s a reasonable chance (especially if you are reading this on your phone) that your breath is shallow, in the upper chest and possibly through the mouth.
Our breath is perhaps the only activity in our body that happens on its own that can also be consciously controlled. Yet it is rare for most of us to inquire how our breath is or consciously control it. Why does this matter?
Because how we breathe impacts how we feel, how we show up in the world, and even the types of thoughts that arise. (Tip: As you read the following paragraphs, explore deliberately breathing faster than usual through your mouth and into your upper chest.)
Deep inside your brain lies a piece of biological hardware known as your insula cortex. It interprets signals from your breathing rhythms, serving as a central hub for somatic (bodily) and interoceptive—or internal—signals.
Image credit: BMJWhen you breathe through the mouth and into the upper lungs, signals are relayed to activate the sympathetic or activating part of your nervous system, creating a cascade effect that communicates to your endocrine system to secrete adrenaline and cortisol—which, in turn, generate measurable shifts in your blood chemistry.
These shifts in blood chemistry impact the emotions you feel and even the tone of thoughts that will arise—like impulsive actions, anxious thoughts, and feelings of frustration. We can fall into a trap as these unproductive thoughts and feelings reinforce or even exacerbate the breath pattern that activates the sympathetic response in the nervous system.
(If you haven’t already, you can let your breathing return to normal. Notice how you feel internally.)Here, the common strategy is to attempt to think our way out of the stress. You may be familiar with tactical mindfulness, cognitive reframes, or thoughts of loving-kindness to change your state of mind. These act as top-down interventions for throwing a wrench into the negative thought spiral. However, it’s possible—and more effective—to shift your breathing pattern to generate calmer thoughts and feelings.
There are important neurological reasons why. Our nervous system consists of 80% of afferent neurons, which move from the body to the brain—in contrast to roughly 20% of efferent neurons, which run in the opposite direction, from the brain to the body.
As a result, so-called bottom-up interventions—or practices that leverage our physiology by consciously shifting our respiratory or visual systems—are 4x more effective at altering our blood chemistry and, therefore, shifting our state.
Embrace state over story
Working with clients, I will often talk about “state before story”—the idea that the stories we tell ourselves and the perspectives we inhabit are a function of our nervous system state.
Thanks to our Sponsor: Future London Academy
Thanks again to today’s sponsor, Future London Academy’s MBA for Design Leaders.
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